SS-31 Research Peptide — Mitochondrial-Targeted High-Purity Compound for Laboratory Use

Product Overview

SS-31 is a research-grade mitochondrial-targeted peptide supplied as a sterile lyophilized powder in sealed vials. Each package contains ten vials, with each vial holding 10mg of the research compound. This product is manufactured exclusively for scientific investigation and in vitro laboratory experimentation.

Key Specifications at a Glance:

• Quantity: 10mg per vial, 10 vials per pack

• Form: Lyophilized (freeze-dried) powder

• Purity: >99% verified by third-party testing

• Molecular Mass: 339.4

• CAS Number: 160698-61-1

• Research Focus: Mitochondrial biology

• Research Use Only: Not for human or animal consumption

Understanding SS-31: The Research Context

SS-31, also known by other designations in scientific literature, is a synthetic peptide specifically designed to target mitochondria. Mitochondria are specialized structures within cells responsible for energy production and numerous other essential cellular functions.

Key Research Interests:

• Mitochondrial function and bioenergetics

• Cellular energy metabolism studies

• In vitro cell culture investigations

• Mitochondrial dynamics and signaling pathways

Researchers utilize SS-31 in controlled laboratory settings to better understand mitochondrial biology and the role of these cellular structures in various physiological processes.

The Significance of Mitochondrial Targeting:
Mitochondria are often described as the powerhouses of cells, generating the energy needed for cellular functions. The ability to direct compounds specifically to mitochondria allows researchers to study these structures with greater precision. SS-31’s targeted nature makes it a valuable tool for investigators focused on mitochondrial research.

Third-Party Testing and Quality Assurance

Every batch of SS-31 undergoes rigorous independent analytical testing to verify identity, purity, and consistency. This third-party testing ensures that researchers receive a product that meets strict quality specifications before it is approved for release.

The testing process includes:

• Identity verification through mass spectrometry

• Purity analysis using high-performance liquid chromatography (HPLC)

• Batch-to-batch consistency checks

• Residual solvent analysis to confirm complete lyophilization

With a verified purity exceeding 99%, SS-31 meets the high standards required for serious laboratory research applications. Each vial contains only the lyophilized research compound with no unnecessary additives, fillers, or excipients.

Chemical and Physical Properties

Molecular Characteristics

SS-31 is a synthetic peptide with a relatively low molecular mass of 339.4 daltons, making it significantly smaller than many other research peptides. This smaller size contributes to its unique properties and targeted mechanism of action.

The compound is registered under CAS number 160698-61-1, a unique identifier that allows researchers to verify they are working with the correct chemical compound when ordering or referencing SS-31 in scientific publications.

Physical Form and Storage

The product is supplied as a lyophilized (freeze-dried) powder within a sterile, sealed vial. Lyophilization preserves the chemical integrity of the peptide by removing water content while maintaining the compound’s structure.

Recommended Storage Conditions:

• Store lyophilized powder at -20°C (-4°F) or below for long-term preservation

• Protect from light exposure

• Keep desiccated to prevent moisture absorption

• Allow vial to reach room temperature before opening to avoid condensation

• Avoid repeated freeze-thaw cycles once reconstituted

Stability Considerations:
SS-31 is generally stable when stored properly in lyophilized form. However, like all peptides, it is susceptible to degradation over time. Researchers should note the manufacturing date and plan experiments accordingly to ensure they are working with material that has been stored under appropriate conditions.

Once reconstituted with an appropriate sterile solvent, the solution should be used promptly according to laboratory protocols.

Intended Use and Regulatory Status

Research Use Only

SS-31 is classified as a research chemical and is intended exclusively for laboratory and in vitro experimentation. This designation means the product is sold strictly for:

• In vitro testing — experiments conducted in controlled laboratory environments

• Cell culture studies — investigating peptide interactions with cellular systems

• Mitochondrial research — studying mitochondrial function and biology

• Analytical research — chemical analysis and characterization studies

• Scientific investigation — basic research into peptide structure and function

Important Regulatory Notice

This product is not a drug, food, cosmetic, or medical device. Bodily introduction of any kind into humans or animals is strictly forbidden by law. The product should only be handled by licensed, qualified professionals working in appropriate laboratory facilities.

The supplier is a chemical supplier, not a compounding pharmacy or outsourcing facility under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act. All product information provided is for educational purposes only and does not constitute medical advice or clinical recommendations.

Handling and Safety Guidelines

Professional Handling Required

SS-31 should only be handled by trained laboratory personnel wearing appropriate personal protective equipment (PPE), including:

• Laboratory coat

• Nitrile gloves

• Safety goggles or face shield

• Appropriate respiratory protection if aerosolization is possible

Reconstitution Protocol

For laboratory use, the lyophilized powder should be reconstituted with a sterile, compatible solvent. Standard practice includes:

1. Allow the sealed vial to reach room temperature — approximately 15-30 minutes

2. Clean the rubber stopper with an alcohol swab

3. Add the calculated volume of solvent to achieve desired concentration

4. Gently swirl or roll the vial between palms — do not shake vigorously to avoid foaming

5. Allow complete dissolution before use — this typically takes 2-5 minutes

Reconstitution Example for SS-31:
For researchers needing a 5mg/mL working solution, add 2mL of sterile solvent to the 10mg vial. For a 10mg/mL solution, add 1mL of solvent. For a 2mg/mL solution, add 5mL of solvent. For a 1mg/mL solution, add 10mL of solvent. Always verify calculations before proceeding with experiments.

Solvent Considerations:
Researchers should determine the appropriate solvent based on their specific experimental protocol. Common options include sterile water for injection, bacteriostatic water, or buffered solutions. The choice of solvent may affect peptide stability and should be validated for each experimental application.

Disposal Considerations

Dispose of SS-31 and any contaminated materials in accordance with federal, state, and local regulations for chemical waste disposal. Do not dispose of in regular trash or down drains unless permitted by local guidelines.

Research Applications

SS-31 is used in various laboratory research contexts, primarily focused on mitochondrial biology. Typical applications include:

Mitochondrial Function Studies:
The primary research interest in SS-31 revolves around its ability to target mitochondria. Researchers use SS-31 to investigate mitochondrial bioenergetics, including ATP production, oxygen consumption, and electron transport chain function.

Cellular Metabolism Research:
Because mitochondria are central to cellular energy metabolism, SS-31 serves as a research tool for studying metabolic pathways and energy homeostasis in controlled cell culture systems.

Mitochondrial Dynamics Investigations:
Mitochondria are dynamic structures that undergo fusion, fission, and movement within cells. SS-31 is used to study these processes and their regulation.

Calcium Handling Studies:
Mitochondria play a crucial role in cellular calcium buffering and signaling. Researchers may use SS-31 to investigate mitochondrial calcium uptake and release mechanisms.

Reactive Species Research:
Mitochondria are both sources and targets of reactive molecules within cells. SS-31 is used in studies examining mitochondrial redox biology and oxidative processes.

Structure-Activity Relationship (SAR) Analysis:
The synthetic nature of SS-31 allows researchers to study how specific structural features contribute to its mitochondrial-targeting properties and biological activity.

Researchers should design their experimental protocols based on peer-reviewed literature and established laboratory practices specific to mitochondrial-targeted peptides.

What Makes This Product Different

Mitochondrial Targeting

Unlike many research peptides that act broadly within cells, SS-31 is specifically designed to target mitochondria. This targeted property distinguishes SS-31 from other research compounds and makes it particularly valuable for investigators focused on mitochondrial biology.

Rigorous Quality Control

Unlike research chemicals sold without verification, SS-31 comes with documented third-party testing for every batch. This commitment to quality assurance gives researchers confidence in the consistency and reliability of their experimental results.

Complete Documentation

Each product listing includes full chemical specifications, including molecular mass and CAS number. This transparency allows researchers to verify the exact compound they are working with.

Appropriate Packaging for Research Use

The sterile, sealed vial packaging protects the lyophilized powder from environmental contaminants. The 10mg concentration is particularly useful for experiments requiring precise, smaller-scale handling.

Batch Traceability

Each package of SS-31 includes batch identification numbers that allow researchers to trace their material back to original manufacturing and testing records. This traceability is essential for reproducible research and quality documentation.

Frequently Asked Questions for Researchers

What is the purity level of SS-31?

Each batch is tested to verify purity exceeding 99%. Individual certificates of analysis are available upon request.

How should the lyophilized powder be stored?

Store at -20°C or below, protected from light and moisture. Avoid repeated freeze-thaw cycles once reconstituted.

What solvent should be used for reconstitution?

Researchers should determine the appropriate solvent based on their specific experimental protocol. Common options include sterile water for injection, bacteriostatic water, or buffered solutions such as phosphate-buffered saline (PBS).

Is this product sterile?

The lyophilized powder is manufactured under aseptic conditions, but researchers should follow standard laboratory practices for handling research chemicals. For cell culture applications, additional filtration using a 0.22-micron filter may be appropriate.

What is the significance of the low molecular mass (339.4)?

The relatively low molecular mass of SS-31 contributes to its unique properties and distinguishes it from larger research peptides. This smaller size is relevant to its mechanism of action and targeting capabilities.

What is the significance of the CAS number 160698-61-1?

The CAS number is a unique identifier for SS-31, allowing researchers to verify they are working with the correct chemical compound when ordering or referencing the peptide in publications.

How does SS-31 differ from other research peptides?

SS-31 is specifically designed to target mitochondria, whereas many other research peptides have different cellular targets or mechanisms of action. This mitochondrial targeting makes SS-31 particularly valuable for researchers focused on mitochondrial biology.

Can SS-31 be used in combination with other research peptides?

Researchers should determine compatibility based on their specific experimental design. Standard laboratory practice includes testing interactions in control experiments before full-scale implementation.

Final Notes for Laboratory Researchers

SS-31 represents a high-purity research tool for qualified professionals conducting legitimate scientific investigations into mitochondrial biology, cellular energy metabolism, and related fields. With documented third-party testing, complete chemical specifications, and appropriate packaging for laboratory use, this product meets the standards expected by serious researchers.

The 10mg vial size is optimized for smaller-scale experiments, preliminary studies, and protocols requiring precise handling. For larger-scale research, multiple vials can be used to achieve the desired quantity.

For research use only. Not for human or animal consumption. Handle only in appropriate laboratory facilities with proper safety equipment and training.